SPECTRUM

Chemical Fact Sheet

Chemical Abstract Number (CAS #) 108463
CASRN 108-46-3
SynonymsResorcinol
1,3-Benzenediol
Resorcin
meta-Dihydroxybenzene
Molecular FormulaC6H6O2

Link to the National Library of Medicine's Hazardous Substances
Database for more details on this compound.

Use IN TANNING; MFR HEXYLRESORCINOL; P-AMINOSALICYLIC ACID; EXPLOSIVES; DYES; IN COSMETICS; AS REAGENT FOR ZINC DYEING & PRINTING TEXTILES; KERATOLYTIC; VET: TOPICAL ANTIPRURITIC & ANTISEPTIC; INTESTINAL ANTISEPTIC CROSS-LINKING AGENT FOR NEOPRENE; RUBBER TACKIFIER; MFR STYPHNIC ACID IN PHOTOGRAPHY CHEMICAL INTERMEDIATE IN SYNTH OF RESORCINOL-FORMALDEHYDE RESINS, RESIN PROGENITORS, WOOD ADHESIVE RESINS Medication: Keratolytic (desquamating agent) Medication: Resorcinol is employed in the treatment of acne, ringworm, psoriasis, eczema, seborrheic dermatitis and other cutaneous lesions Used as tire and rubber adhesives also as wood adhesives; as ultraviolet absorbers (resorcinol derivatives); and as starting materials for the preparation of dyestuffs. Resorcinol is an indirect food additive polymer for use as a basic component of single and repeated use food contact surfaces. For use only as a reactive adjuvant substance employed in the production of gelatin-bonded cord composition for use in lining crown closures.
Consumption Patterns 42% FOR RESORCINOL-FORMALDEHYDE RESINS AND RESIN PROGENITORS; 31% EXPORTED; 15% FOR WOOD ADHESIVE RESINS; 12% FORMISC APPLICATIONS (1970) In 1977, the United States use of resorcinol was 65% in the manufacture of rubber products, 20% in wood adhesives, and 15% for miscellaneous uses.
Apparent Color WHITE NEEDLE-LIKE CRYSTALS ; NEEDLES FROM BENZENE; PLATES FROM WATER ; RHOMBIC TABLETS & PYRAMIDS ; POWDER
Odor FAINT, CHARACTERISTIC ODOR
Boiling Point 280 DEG C
Melting Point 109-111 DEG C
Molecular Weight 110.11
Density 1.2717
Odor Threshold Concentration Odor threshold concentration (detection): 6.0 mg/l
Sensitivity Data Irritant to skin and eyes
Environmental Impact Resorcinol may be released to the environment in waste effluents associated with coal gasification and conversion, coal-tar production, and shale oil processing and from the combustion of wood and tobacco. If released to the atmosphere, resorcinol is expected to degrade rapidly (estimated half-life of 1.9 hr) by reaction with photochemically produced hydroxyl radicals. Night-time reaction with nitrate radicals may also contribute to its atmospheric transformation. If released to soil or water, biodegradation is expected to be an important fate process based on the results of a number of biological screening studies which have suggested that resorcinol is readily biodegradable. By analogy to other phenol compounds, resorcinol may react relatively rapidly in sunlit natural water with photochemically produced oxidants such as hydroxyl and peroxy radicals. Resorcinol is expected to leach readily in soil; however, leaching may not be important if concurrent biodegradation occurs at a rapid rate. Occupational exposure may occur through dermal contact or inhalation at sites where the compound is produced or used as a chemical intermediate, or at sites involved with coal conversion. Exposure to the general population may occur through the inhalation of wood and tobacco smoke and through direct dermal contact with topical medicinal products containing resorcinol.
Environmental Fate TERRESTRIAL FATE: The major degradation process for resorcinol in soil is expected to be biodegradation. A number of biological screening studies have found resorcinol to be readily biodegradable. In a laboratory soil degradation study using a chernozem soil which had been exposed to the coking industry, 500 ppm resorcinol was degraded in 2 days . Resorcinol is expected to leach readily in soil; however, leaching may not be important if concurrent biodegradation occurs at a rapid rate. AQUATIC FATE: The major degradation processes for resorcinol in natural water may be biodegradation and photooxidation. A number of biological screening studies have found resorcinol to be readily biodegradable. By analogy to other phenol compounds, resorcinol may react relatively rapidly in sunlit natural water with photochemically produced oxidants such as hydroxyl and peroxy radicals; typical half-lives for hydroxyl radical and peroxy radical reaction with phenol are on the order of 100 and 19.2 hours of sunlight, respectively . Aquatic hydrolysis, volatilization, adsorption to sediments, and bioconcentration are not expected to be important. ATMOSPHERIC FATE: Based upon an extrapolated vapor pressure of 3.84X10-4 mm Hg at 25 deg C(1,SRC), resorcinol can be expected to exist almost entirely in the gas-phase in the ambient atmosphere(2,SRC). Gas-phase resorcinol is expected to degrade rapidly in air by reaction with photochemically produced hydroxyl radicals; the half-life for this reaction in an average atmosphere has been estimated to be 1.9 hr(3,SRC). Night-time reaction with nitrate radicals may also contribute to the atmospheric transformation of resorcinol.
Drinking Water Impact GROUND WATER: Resorcinol was found as a pollutant in filtered ground water at a waste treatment plant . SURFACE WATER: Resorcinol was found as a pollutant in filtered surface water at a waste treatment plant . EFFL: HAS ALSO BEEN FOUND IN EFFLUENTS RESULTING FROM PRODUCTION OF COAL-TAR CHEM No concn given. The concn of resorcinol in the condensate water from a coal gasification facility in Grand Forks, ND ranged from not detected (no analytical detection limit reported) to 60 ppm between Jun 1980 and Apr 1982 . A resorcinol level of 1000 ppm was detected in wastewater from a synthetic coal conversion process . Resorcinol has been found in wood smoke and cigarette smoke and in effluents generated from the production of coal-tar chemicals .

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