|Chemical Abstract Number (CAS #)||
|Synonyms||Ethyl acetate||Acetic acid, ethyl ester
||EPA Method 8260|
Link to the National Library of Medicine's Hazardous Substances
Database for more details
on this compound.
|Use|| ARTIFICIAL FRUIT ESSENCES; SOLVENT FOR NITROCELLULOSE, VARNISHES,
LACQUERS, AEROPLANE DOPES; MANUFACTURE OF SMOKELESS POWDER,
ARTIFICIAL LEATHER, & PHOTOGRAPHIC FILMS & PLATES, ARTIFICIAL SILK,
PERFUMES; CLEANING TEXTILES; PHARMACEUTIC AID (FLAVOR)
SYNTHETIC FLAVORING; USED IN FOODS
EXTRACTION SOLVENT FOR N-NITROSODIETHANOLAMINE.
FOR CONTACT LENS MOLD RELEASE.
SOLVENT FOR COATINGS (EG, SHELLAC) & PLASTICS (EG, VINYL RESINS); OTHER
SOLVENT USES (EG, INKS); CHEM INTERMEDIATE; AROMA ENHANCER IN GRAPE
Solvent in production of adhesives, fingernail polishes; extraction solvent in production of
pharmaceuticals and foods; carrier solvent for herbicides; component of lacquer thinner.
MEDICATION: IT HAS BEEN USED INTERNALLY IN A DOSE OF 1 TO 2 CC AS
CARMINATIVE & ANTISPASMODIC, ALSO EXTERNALLY AS COUNTERIRRITANT .
/Used as component of base sheet (cellophane) or as coatings applied to impart desired
/Used as diluents in inks for marking fruits and vegetables.
Splitting influenza viruses for the manufacture of vaccines/.
|Consumption Patterns|| SOLVENT FOR: COATINGS (EG, SHELLAC), 65%; PLASTICS (EG, VINYL
RESINS), 12%; OTHER SOLVENT USES (EG, INKS), 20%; CHEM INTERMEDIATE, 3%
Lacquers and enamels, 60%; inks, 15%; miscellaneous, 25% (1983) estimate
CHEMICAL PROFILE: Ethyl Acetate. Coatings solvent, 40%; exports, 38%; miscellaneous
solvent uses, 12%; plastics, 8%; chemical synthesis, 2%.
CHEMICAL PROFILE: Ethyl acetate. Demand: 1988: 210 million lb; 1989: 210 million lb; 1993
/projected/: 220 million lb. (Includes exports, but not imports, which totaled 30 million lb last
|Apparent Color|| CLEAR LIQUID
|Odor|| CHARACTERISTIC ETHER-LIKE ODOR REMINISCENT OF PINEAPPLE. ;
Fragrant odor ; Fruity odor
|Boiling Point|| 77 DEG C
|Melting Point|| -83 DEG C
|Molecular Weight|| 88.10
|Density|| Sp gr: 0.902 AT 20 DEG C/4 DEG C
|Odor Threshold Concentration|| DETECTION IN AIR IS 0.006 TO 0.686 MG/L; DETECTION IN WATER IS 5 PPM.
Detection in air: 3.6-1.120 mg cu/m
0.0196 mg/cu m (low odor); 665.0 mg/cu m (high odor); 350 mg/cu m (irritating concn)
|Sensitivity Data|| Irritating to mucous surfaces, particularly the eyes, gums and respiratory passages .
|Environmental Impact|| Ethyl acetate is emitted to the air and discharged into wastewater during its production
and use as an industrial solvent and in organic synthesis. It is also released into the air during the
formation of whiskey and beer. If released into water ethyl acetate will be lost primarily by
evaporation (half-life 10 hr in a typical river) and biodegradation. While ethyl acetate is readily
biodegraded in most aquatic tests, the rate in natural waters is unknown. Bioconcentration in fish
will be insignificant. If released on land, ethyl acetate will partially evaporate and partially leach
into the ground. Biodegradation will probably occur both in soil and groundwater, however,
experimental data are lacking. In the atmosphere, ethyl acetate will react with photochemically
produced hydroxyl radicals (half-life 8.3 days). A few percent an hour will disappear under
photochemical smog situations. Humans will be exposed to ethyl acetate in the workplace, by
ingesting certain food items (eg beer) of which it is a natural component, and while using
consumer products such as airplane dope and nailpolish remover.
|Environmental Fate|| TERRESTRIAL FATE: If released on land, ethyl acetate will be lost by evaporation and
leaching into groundwater. Biodegradation should also occur because it is readily biodegradable
in both aerobic and anaerobic systems, but rates for these processes in natural systems are not
AQUATIC FATE: If released in water, ethyl acetate will primarily be lost by volatilization
(half-life 10 hr from a typical river). Biodegradation should also occur, but rates of biodegradation
relevant to natural waters are lacking. Ethyl acetate would not be expected to adsorb to sediment
or particulate matter.
ATMOSPHERIC FATE: Ethyl acetate will react with photochemically produced hydroxyl
radicals (clean atmosphere half-life 8.3 days; moderately polluted half-life 2.1 days). Under
photochemical smog conditions 1.9-3.4% of the ethyl acetate is lost per hour.
|Drinking Water Impact|| DRINKING WATER: Detected, not quantified in 3 New Orleans drinking water
plants . Detected in drinking water-no levels given . GROUND WATER: Not detected in
aquifer polluted by a paint factory even though ethyl acetate was stored in buried tanks that
leaked . SURFACE WATER: USA-14 Heavily industrialized river basins in USA (204
sites)-only 1 site (Delaware River Basin) positive-1 ppb . Hayashida River in Tatsumo City,
Japan (site of leather industry) 585 ppb .
EFFL: Oil refinery final effluent-detected, not quantified . Detected, not quantified in effluent
from sewage treatment plants .
Effluent gas from the metal painting factory and from the lumber painting factory contained ethyl