SPECTRUM

Chemical Fact Sheet

Chemical Abstract Number (CAS #) 59507
CASRN 59-50-7
Synonymsp-Chloro-m-cresol
4-Chloro-3-methylphenol
Phenol, 4-chloro-3-methyl-
Chlorophenol, 4-, methyl, 3-
Analytical Methods EPA Method 604
EPA Method 625
EPA Method 8040
EPA Method 8270
Molecular FormulaC7H7ClO

Link to the National Library of Medicine's Hazardous Substances
Database for more details on this compound.

Use EXTERNAL GERMICIDES; PRESERVATIVE FOR GLUES, GUMS, PAINTS, INKS, TEXTILE & LEATHER GOODS MEDICATION: TOPICAL ANTISEPTIC; MEDICATION (VET): HAS BEEN USED AS TOPICAL ANTISEPTIC Used as disinfectant MEDICATION (VET): IN TOPICAL MEDICAMENTS & IN INTRAUTERINE LUBRICANTS AS ANTISEPTIC & PRESERVATIVE (0.1-0.2% CONCN). CHLOROCRESOL & CHLORACETAMIDE ARE USED IN MEDICATIONS, GLUES, & COSMETICS AS PRESERVATIVES. Used in injectable formulations as preservative. CHLOROCRESOL (P-CHLOROMETACRESOL) WAS FORMERLY UTILIZED AS PRESERVATIVE & ANTIFUNGAL AGENT IN EYEDROPS Fungicide
Apparent Color DIMORPHOUS CRYSTALS; NEEDLES FROM PETROLEUM ETHER; WHITE OR SLIGHTLY PINK CRYSTALS
Odor SAID TO BE ODORLESS WHEN VERY PURE, BUT USUALLY A PHENOLIC ODOR PERSISTS
Boiling Point 235 DEG C
Melting Point 66-8 deg C
Molecular Weight 142.58
Odor Threshold Concentration 0.1 mg/kg (detection in water)
Sensitivity Data IRRITANT TO SKIN. Not irritating to skin in concn of 0.5 to 1.0% in alcohol.
Environmental Impact Environmental release of 3-methyl-4-chlorophenol may occur through inadvertent formation in waters (potable water, wastewater, cooling water) which have undergone chlorination treatment and by evaporation or waste releases from product formulation or end-products containing 3-methyl-4-chlorophenol. If released to the atmosphere, 3-methyl-4-chlorophenol will degrade rapidly (half-life of 1.1 days) via reaction with hydroxyl radicals. If released to water, photolysis and biodegradation appear to be capable of degrading 3-methyl-4-chlorophenol, although sufficient data are not available to predict rates at which these processes may occur in the environment. Various screening tests have demonstrated that 3-methyl-4-chlorophenol is readily biodegradable under aerobic conditions, but not degradable under anaerobic conditions. Aquatic hydrolysis, bioconcentration and volatilization are not important. If released to soil, leaching is likely to occur along with aerobic biodegradation. In various groundwaters where aerobic degradation is not viable, 3-methyl-4-chlorophenol may be relatively persistent. Exposure of 3-methyl-4-chlorophenol to the general population may occur through consumption of contaminated drinking water where the chemical has been inadvertently formed during chlorination treatment. Dermal and inhalation exposure may be possible through use of consumer products formulated with 3-methyl-4-chlorophenol.
Environmental Fate Chlorinated phenols will undergo photolysis in aqueous solutions as a result of ultraviolet irradiation and that photodegradation leads to the substitution of hydroxyl groups in place of the chlorine atoms with subsequent polymer formation. Chlorinated phenols TERRESTRIAL FATE: 3-Methyl-4-chlorophenol appears to be susceptible to significant leaching in soil based on one experimental adsorption study , an estimated Koc of 50, and its detection in groundwater. Biodegradation is probably the only relevant degradation mechanism in soil. Various screening tests have demonstrated that 3-methyl-4-chlorophenol is readily biodegradable under aerobic conditions, but not degradable under anaerobic conditions. Therefore, in various groundwaters where aerobic degradation is not viable, 3-methyl-4-chlorophenol may be persistent. AQUATIC FATE: Photolysis and biodegradation appear to be the important environmental fate processes for 3-methyl-4-chlorophenol in water, although sufficient data are not available to predict rates at which these processes may occur in the environment. 3-Methyl-4-chlorophenol absorbs uv light in the sunlight spectrum; in addition, similar compounds have been shown to photodegrade experimentally. Various screening tests have demonstrated that 3-methyl-4-chlorophenol is readily biodegradable under aerobic conditions, but not degradable under anaerobic conditions. Aquatic hydrolysis, bioconcentration and volatilization are not important. ATMOSPHERIC FATE: If released to the atmosphere, 3-methyl-4-chlorophenol should predominantly exist in the vapor phase. The dominant environmental fate process in the atmosphere will be the vapor phase reaction with hydroxyl radicals which are photochemically formed by sunlight. The half-life of this reaction in a typical ambient atmosphere has been estimated to be 1.1 days.
Drinking Water Impact DRINKING WATER: Qualitative detection of 3-methyl-4-chlorophenol has been reported for an unspecified drinking water . 3-Methyl-4-chlorophenol was identified in groundwater from 11 drinking water wells in areas of China irrigated with sewage effluents . SURFACE WATER: 3-Methyl-4-chlorophenol was not detectable at various monitoring locations on Lake Erie or Lake Michigan . EFFL: CHLORINATION REACTION YIELDS OF CHLOROORGANIC PRODUCTS IN COOLING WATER & SEWAGE EFFLUENTS ARE 0.5-3.1% (AS CL) IN STUDIES OF TYPICAL PROCESSES. ANY OR ALL OF THE MANY CHLORINATION REACTIONS MAY OCCUR DURING WATER CHLORINATION. Chlorinated municipal sewage effluents have been observed to contain 3-methyl-4-chlorophenol concentrations of approximately 2 ppb . 3-Methyl-4-chlorophenol levels of 73 ng/l, 154 ng/l, and 0.22 mg/kg (dry wt) were detected in a final effluent from a treatment works, in a soil leachate, and in a wastewater sludge, respectively, from the United Kingdom . Positive detections have been reported for raw and treated wastewaters from the auto, iron and steel mfg, aluminum forming, foundries, metal finishing, photographic, pharmaceutical mfg, paint and ink formulation, soap and detergent mfg, and textile industries; mean concn varied widely from 0.01 to 100,000 ug/l . 3-Methyl-4-chlorophenol has been detected in the stack effluent from a municipal waste incinerator .

DISCLAIMER - Please Read

Florida-Spectrum List of Services
Florida-Spectrum Homepage